https://www.selleckchem.com/pr....oducts/chroman-1.htm
Sox10 was found to bind directly to the Cdh19 promoter. Cdh19 knockdown resulted in retarded sacral NCC migration in vitro and ex vivo, whereas re-expression of Cdh19 partially rescued the retarded migration of mutant sacral NCCs in vitro. Cdh19 formed cadherin-catenin complexes, which then bound to F-actin of the cytoskeleton during cell migration. Cdh19 is a direct target of Sox10 during early sacral NCC migration towards the hindgut and forms cadherin-catenin complexes which interact with the cytoskeleton in migrating cells. Elucid
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