https://www.selleckchem.com/products/pt2399.html
However, endocytosis is not a final fate. Once internalized into endosomes, IChs are either sorted to lysosomes for degradation or recycled back to the plasma membrane. Rab proteins are crucial participants during these turnover steps. In this review, we describe the major ICh endocytic pathways, the signaling inputs triggering ICh internalization, and the key mediators of this essential cellular process.Despite multitudes of reports on cancer remedies available, we are far from being able to declare that we have arrived at that defining
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