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The as-synthesized DOX/PEI@TeNP system can produce reactive oxygen species (ROS) under near-infrared (NIR) light irradiation and features a high photothermal conversion efficiency due to its strong NIR absorbance. Therefore, this study provides an effective strategy for the effective design of nano-drugs, which can be used for the accurate chemical-photothermal synergistic therapy of tumors.Modulating the hypoxic microenvironment is the priority for tumor treatment. Cytometalated iridium(iii)-metformin conjugates were synthesized for tr
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