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Finally, connected loss of PTEN with FASN overexpression had been connected with lethality as evaluated in 660 prostate cancer tumors clients with 14.2 years of median follow-up. Taken collectively, these findings reveal that de novo lipogenesis plays a role in the intense phenotype caused by Pten loss in murine prostate and focusing on Fasn may lower the unpleasant potential of prostate cancer tumors driven by Pten reduction. © 2020 The Authors. The Jour
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