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15-1.71; P = 0.001) were independent risk factors for the presence of HRV. The negative predictive value was 95%, when albumin-platelet-portal vein diameter varices scores (APP score) were 0.24. One hundred twenty-five of 221 (56.6%) patients met an APP score 0.24 with a 4.8% HRV miss rate. In the validation cohort, 59 of 113 (51.3%) patients met the APP score 0.24 with a 1.7% HRV miss rate. APP score is a potential model for safely screening HRV and sparing EGDs in patients with HBV-related cACLD. APP score is a po
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