https://www.selleckchem.com/pr....oducts/Nobiletin(Hex
We demonstrated that effects of serum matrix on molecular interactions between drugs and target proteins can be investigated in real time using magnetic bio-sensing techniques. A giant magneto-resistive (GMR) sensor was used on which target proteins were fixed and superparamagnetic nanoparticles (diameter 50 nm) conjugated with drug were used in phosphate buffer, with and without serum. In this study, the following drug-protein pairs were investigated quercetin and cAMP-dependent protein kinase A (PKA), Infliximab
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