https://influenzavirussignal.c....om/index.php/prognos
We found that endogenous TLR7 ligands, miR-29 and miR-Let7b, had been markedly increased in PsA when compared with osteoarthritis (OA) synovial fluid (SF)s. We revealed that intradermal (i.d.) miR-Let7b injection presented epidermis irritation, which was characterized by increased Th1 cells, CD68+ M1 macrophages, and transcriptional upregulation of glycolytic mediators, GLUT1, C-MYC, and HIF1α. Development of skin Th1 cells driven by miR-Let7b has a
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