https://www.selleckchem.com/pr....oducts/pf-05221304.h
Stable expression of a constitutive active mutant of STAT3 prevented the reduction of cell viability by HsA. Finally, HsA enhanced the sensitivity of sorafenib-mediated cytotoxicity by exaggerating oxidative stress and Y705 dephosphorylation of STAT3. Therefore, HsA will be a promising candidate to induce apoptosis of HCC cells via downregulating STAT3 and sensitizing conventional chemotherapeutic agents.Organophosphorus polyurethane ionomers (AEPA-PU) based on aminoethers of ortho-phosphoric acid (AEPA) were obtained and studied as
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