https://www.selleckchem.com/pr....oducts/ly3023414.htm
Phagocytosis is the key mechanism for host control of Pseudomonas aeruginosa, a motile gram-negative, opportunistic bacterial pathogen, which frequently undergoes adaptation and selection for traits that are advantageous for survival. One such clinically relevant adaptation is the loss of bacterial motility, observed within chronic infections, that is associated with increased antibiotic tolerance and phagocytic resistance. Previous studies using phagocytes from a Leukocyte Adhesion Deficiency type 1 (LAD-I) patient identified CD18 as
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