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009). SUVmax of 18 F-FAMT was significantly higher in high PD-L1 (P less then 0.001), high CD8 (P = 0.012), and hot tumor groups (P = 0.028) than in other groups. High SUVmax of 18 F-FAMT (≥ 4.15) was identified as the only predictor of hot tumor immune status. High PET tracer uptake was significantly associated with cancer aggressiveness and hot tumor immune status in ESCC. PET imaging may be an effective tool to predict tumor immune status in ESCC with respect to immune checkpoint inhibitor sensitivity. This article is protected by
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